検索結果

Search Results for " AP 10 "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T23027	MRT-10		Hedgehog/Smoothened
	MRT-10 is a Smoothened (Smo) receptor antagonist.		Hedgehog/Smoothened
T8425	Linoleoyl Ethanolamide		TRP/TRPV Channel
	Linoleoyl Ethanolamide is an endocannabinoid agent. It acts by binding to TRPV1 increasing ERK phosphorylation and AP-1 dependent transcription in CB-receptor in an independent manner.		TRP/TRPV Channel
T4567	Sulfaphenazole	Plisulfan,Raziosulfa,Depocid,Depotsulfonamide	P450 , Antibacterial
	Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1...		P450 , Antibacterial
T25573	Ketomethylenebestatin
	Ketomethylenebestatin is a carba-analog of bestatin，the aminopeptidase (AP) inhibitor. Ketomethylenebestatin is 10 fold less effective as an inhibitor of aminopeptidases than bestatin.
T83856	AP-1
	AP-1, a miniaturized proteolysis-targeting chimera (PROTAC) incorporating an anaplastic lymphoma kinase (ALK) ligand connected to (±)-thalidomide via an ultrashort linker, effectively degrades ALK fusion proteins such as...
T70063	GYKI 52466 HCl
	GYKI 52466 is an allosteric AMPA receptor antagonist. It selectively inhibits AMPA-induced inward currents (IC50 = 7.5 µM) over NMDA- or GABA-induced inward currents in primary rat hippocampal neurons at 50 µM but also i...

Compounds

MRT-10

T23027

Synonym:

Target: Hedgehog/Smoothened

Linoleoyl Ethanolamide

T8425

Synonym:

Target: TRP/TRPV Channel

Sulfaphenazole

T4567

Synonym: Plisulfan,Raziosulfa,Depocid,Depotsulfonamide

Target: P450, Antibacterial

Ketomethylenebestatin

カタログ番号	製品名	別名	ターゲット
TQ0185	14-Deoxy-11,12-didehydroandrographolide	AP10,14-dehydro Andrographolide	NF-κB
	14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.		NF-κB
TN5639	Rocaglaol	Ferrugin,Aglaiastatin A
	Rocaglaol is a potent anticancer drug that induces apoptosis of LNCaP cells through the mitochondrial pathway and its G2/M-phase cell cycle arrest is associated with the down-regulation of Cdc25C and the dephosphorylatio...

天然物製品

14-Deoxy-11,12-didehydroandrographolide

TQ0185

Synonym: AP10,14-dehydro Andrographolide

Target: NF-κB

Rocaglaol

TN5639

Synonym: Ferrugin,Aglaiastatin A

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02300	BIN1 Protein, Human, Recombinant (His)	Human	E. coli
	Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicat...
TMPY-01751	DR3/TNFRSF25 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	DR3/TNFRSF25 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
TMPY-00961	ADAM15 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ADAM15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is Q13444-10.
TMPY-05760	DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
	DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.

BIN1 Protein, Human, Recombinant (His)

TMPY-02300

Species: Human

Expression System: E. coli

DR3/TNFRSF25 Protein, Human, Recombinant (hFc)

TMPY-01751

Species: Human

Expression System: HEK293 Cells

ADAM15 Protein, Human, Recombinant (His)

TMPY-00961

Species: Human

Expression System: HEK293 Cells

DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated

TMPY-05760

Species: Human

Expression System: HEK293 Cells